During the high season of influenza, many people are "recruited", and oseltamivir, as a flu-specific drug, has once again attracted people’s attention. In the investigation, the reporter found that in addition to some patients who have been diagnosed with influenza taking this medicine, many people will take this medicine if they have influenza patients or have been exposed to influenza patients at home, and even some people will buy oseltamivir for just a common cold. Experts remind that drugs are not only an important means of "treating diseases", but also an important factor of "causing diseases".
The flu "magic medicine" smashed the circle of friends and the pharmacy was almost out of stock.
"The girl got caught, and when she bought the medicine, she found that the medicine was almost out of stock. Super expensive, 68 yuan a box, you can buy a big elbow! "
"Hermes (oseltamivir) in medicine, the flu virus is terrible, with a high fever of 40.2 C, a box of 55 yuan, and a family eats almost two boxes a day."
"This wave of flu is a high fever. The doctor said that this medicine can only be eaten for 3 days! The prostitute didn’t burn after drinking for a day! " … …
With the intensification of the influenza epidemic, the sales of oseltamivir in various places may be even tighter, and some of them are out of stock. Secondly, the out-of-stock of oseltamivir is not the key point. The key point is that after the toss of the flu, the circle of friends has already begun to be restless. The circle of friends on WeChat has been screened by the flu "magic medicine" oseltamivir, and oseltamivir has long been a "red man" in the pharmaceutical industry. It is better to show off oseltamivir.
Yesterday, the reporter visited 10 pharmacies in the city and learned that there are five kinds of oseltamivir mainly sold in pharmacies: oseltamivir Kewei phosphate granules (15mg×10 bags), oseltamivir Kewei phosphate granules (15mg×12 bags), oseltamivir Kewei phosphate capsules (75mg×6 capsules) and oseltamivir Kewei phosphate capsules (75mg× 12 bags). Among them, Kewei brand is domestic medicine, while Tamiflu is imported medicine, and the price ranges from 50 yuan to 220 yuan.
Among the 10 pharmacies, only two pharmacies said that the specifications were complete and the goods were sufficient. The other pharmacies all said that some specifications were out of stock, and the inventory of individual specifications was not much. "Our pharmacy oseltamivir usually can’t sell a few boxes a month. Before the arrival of the flu season, some people have started to stock up, and the sales volume has started to rise. In the flu season, they can usually sell about 20 boxes a day, and at most they sell 40 boxes a day. From January to now, they have sold almost 200 boxes." The manager of a large chain pharmacy branch in Yucai Street told the reporter.
Take oseltamivir, the "magic medicine" for influenza and cold.
The reason why oseltamivir is so popular now is that people use oseltamivir no matter what kind of cold they have.
Under normal circumstances, if you catch a cold, you will be fine in a week or so. But Ms. Li has had a cold for two weeks, and the symptoms have not completely disappeared.
More than 10 days ago, Ms. Li had dinner with several girlfriends, and then they sang songs for most of the night. Maybe it was fatigue or catching a cold. The next day, Ms. Li’s throat was dry, her head was dizzy, and her nose began to run.
Ms. Li bought some oseltamivir from a drugstore near her unit. "The circle of friends and the internet have all been screened by oseltamivir. Now it is also the season with high incidence of influenza. I thought I had the flu, so I didn’t go to the hospital and bought some medicine myself." Ms. Li said, "What I didn’t expect was that eating for a few days had no effect." In desperation, accompanied by her lover, Ms. Li came to the Respiratory Department of the Provincial People’s Hospital. Through examination, she found that Ms. Li was just a common cold and did not have the flu. Because there was no symptomatic medication, her lungs had become inflamed. Because of her serious illness, the doctor had to advise her to be hospitalized.
Ms. Li’s experience is only a microcosm. A week ago, Mr. Xie’s daughter, who lives in Chang ‘an District, suddenly felt bored and kept coughing, so he took her to the community hospital to see a doctor. "When the doctor finished the examination and said that my daughter had a common cold, he gave us some cold medicine, but I saw that all the friends in the circle were saying that oseltamivir was amazing, so I went to the pharmacy to buy a box of oseltamivir for my daughter, because the children in the pharmacy were out of stock at that time." Mr. Xie said that he later learned from the Internet that oseltamivir was only useful for the flu and had no effect on the common cold. Mr. Xie immediately asked his daughter to stop taking the medicine.
In the investigation, the reporter found that there are not a few people like Ms. Li and Mr. Xie. Except for some patients who have been diagnosed with influenza who are taking oseltamivir, many people will take oseltamivir for prevention if they have influenza patients at home or have been in contact with influenza patients. Even some people will buy oseltamivir for just a common cold. At the same time, oseltamivir, a prescription drug, is easily available in various pharmacies.
Although it is a prescription drug, it can be easily bought without a prescription.
Yesterday morning, the reporter went to a pharmacy on Zhongshan Road. After explaining his purpose to the pharmacy sales staff, the sales staff quickly introduced him to the reporter.
"What kind of oseltamivir do you want, for children or adults?"
"For adults."
"Imported or domestic?"
"Domestic products will do."
"Do you want 6 capsules or 10 capsules, 6 capsules are 118 yuan, 10 capsules are 168 yuan, and 10 capsules can just eat for 5 days."
"I’m just a precaution. I just need 6 capsules."
"Take it once that day, just one pill at a time."
Subsequently, the reporter went to the payment office under the guidance of the sales staff and paid for the medicine smoothly. After that, the reporter went to three pharmacies and got the medicine smoothly without showing the doctor’s prescription.
Oseltamivir is also sold online, but it can only be purchased with a prescription. The reporter opened the mobile phone JD.COM APP to search for oseltamivir, and soon various brands and specifications of oseltamivir were displayed. Click on an oseltamivir window, and two options are displayed in the lower right corner, namely, joining the drug list and making an appointment immediately. Select make an appointment immediately to enter the page of filling in the order, which shows that prescription drugs need to be made by real name, and there is an option of submitting an appointment in the lower right corner. In the case of filling in the basic information but not the prescription information, the pop-up prompt will pop up if you choose to submit an appointment. The drug must be made by appointment. Please upload the prescription or fill in the disease information.
"magic medicine" should not be eaten indiscriminately, but should follow the doctor’s advice
"oseltamivir is mainly used for the treatment and prevention of influenza A and influenza B. It is ineffective for viruses that cause the common cold and is ineffective for bacterial infections complicated by influenza. Therefore, not all colds are suitable for use. " Shen Yanhong, director of the Clinical Pharmacy Department of Hebei Chest Hospital, solemnly reminded.
According to Shen Yanhong, oseltamivir is a neuraminidase inhibitor, which acts on neuraminidase specifically in view of the dependence of influenza virus on neuraminidase, thus inhibiting the continuous replication and further spread of mature influenza virus and playing a role in treating influenza. There is no way for oseltamivir to kill the virus directly, but its function is to inhibit neuraminidase, so that the influenza virus can not get away from infected cells and delay the spread of the virus. Therefore, the time of taking oseltamivir is very important, and the best effect is taken within 48 hours of onset. After more than 48 hours, the influenza virus has produced a sufficient number of offspring viruses, and the effect of taking specific drugs will be discounted. Because rhinovirus, coronavirus and respiratory syncytial virus that cause common cold have no neuraminidase, oseltamivir cannot be used to treat common cold.
"China’s drugs are classified into prescription drugs and over-the-counter drugs." Shen Yanhong said that prescription drugs are drugs that are approved by the state drug supervision and administration department and can only be prepared, purchased and used with the prescription of a licensed doctor or a licensed assistant doctor. The national drug supervision and administration department stipulates all kinds of drugs with many pharmacological effects, severe diseases and easy adverse reactions as prescription drugs, which can be used by patients under the guidance of doctors.
Shen Yanhong suggested that patients with influenza should be treated with oseltamivir as soon as possible. Patients with severe or high-risk factors of severe influenza should be given empirical anti-influenza virus treatment as soon as possible, without waiting for the virus test results. For close contacts with high-risk factors of severe influenza, and those who have not been vaccinated or have not gained immunity after vaccination, it is recommended to take drugs after exposure, not later than 48 hours after exposure.
Shen Yanhong reminded that oseltamivir is a prescription drug. In order to ensure the safety of drug use, it is necessary to purchase drugs in social pharmacies with the help of doctors’ prescriptions and under the guidance of doctors and pharmacists. You can’t buy drugs at will and treat yourself at will. You must follow the doctor’s advice. It should be emphasized here that drug prevention cannot replace vaccination, and influenza vaccination is the most effective means to prevent influenza.
Drugs "cure diseases" will also "cause diseases"
"When we use drugs, we will inevitably encounter adverse drug reactions. The medical community has a long-term understanding of adverse drug reactions." Shen Yanhong said that some drugs have been fully tested in clinical trials, or have been on the market for a long time, have more experience in use, and have a comprehensive understanding of adverse reactions, and there are many adverse reactions listed in their instructions; After many years of use, some drugs will find untoward reactions according to a large number of usage data. Therefore, when using any drugs, we should closely observe the drug use to prevent the occurrence of adverse reactions and ensure the safety of drug use. Once adverse drug reactions occur, stop using drugs in time, seek medical treatment nearby and actively treat them.
According to Shen Yanhong, the overall safety of oseltamivir is good, and the most common adverse reactions are gastrointestinal reactions such as nausea and vomiting. When taken with food, it can improve patients’ tolerance to oseltamivir and reduce gastrointestinal discomfort. Occasionally, it can also cause rare adverse reactions such as nosebleed, bronchitis, insomnia, dizziness, etc., which are relatively mild and can generally be relieved by themselves without affecting medication. "However, there are also newly reported cases of adverse reactions of oseltamivir in clinical or literature reports." Shen Yanhong said that a woman prescribed oseltamivir capsules after going to the clinic for flu. After taking the medicine for about one hour, she developed severe pain in her upper abdomen, accompanied by sweating and dizziness. The blood pressure was measured at 120/76mmHg, and there was no obvious relief after taking Kangfuxin liquid orally. After stopping taking the medicine, the symptoms disappeared, and the above symptoms did not appear again, so "the medicine is not only ‘ Treatment ’ An important means, but also ‘ Pathogenicity ’ An important factor. "