标签： 西安耍耍论坛

On the evening of November 14th, Chengdu held a press conference on epidemic prevention and control. Huang Hui, deputy director of Chengdu Health and Health Commission, said that from 0: 00 to 24: 00 on November 13th, there were 99 new cases of local infection in Chengdu. 20 cases were infected from other provinces (returned) and 79 cases were newly infected in the province.

Huang Hui introduced that on November 11th, the State Council issued the Notice on Further Optimizing the Prevention and Control Measures of COVID-19 Epidemic scientifically and accurately, and announced 20 measures to further optimize the prevention and control work. In accordance with the requirements of epidemic prevention, economic stability and safe development, Chengdu has effectively coordinated epidemic prevention and control and economic and social development. Adjust management measures as required.

In addition, the city’s normalized nucleic acid testing point mixed inspection free testing service was extended to November 30.

Chengdu Municipal Bureau of Commerce: Focusing on Twenty Measures   Further optimize the implementation of prevention and control requirements in the business field.

Li Xiaoyong, deputy director of Chengdu Municipal Bureau of Commerce, said that the commerce and trade industry is closely related to citizens’ lives. Focusing on the 20 measures, Chengdu will further optimize the implementation of prevention and control requirements in the commerce and trade sector, refine the guidelines for epidemic prevention and control in the commerce and trade industry, do a good job in epidemic prevention and control in key places, and compact the responsibility.

The first is to strengthen the prevention and control of key places. Enter shopping malls, supermarkets, restaurants, farmers’ markets and other key places, and strictly implement measures such as temperature measurement, code scanning, code lighting, checking communication itinerary cards and negative proof of nucleic acid testing.

The second is to strengthen nucleic acid monitoring of key populations. Continue to strengthen the nucleic acid monitoring of employees in bars, large-scale agricultural products wholesale markets and cargo handlers in wholesale markets, urge the daily implementation and daily inspection requirements, guide personal protection, and reduce the risk of epidemic spread.

Third, strictly follow the work plan of epidemic prevention and control in Chengdu’s commerce and trade industries and the guidelines for epidemic prevention and control in key commerce and trade industries, implement the requirements of normalized prevention and control, and do a good job in health monitoring, nucleic acid detection and investigation of employees in 30,000 industries. Supervise enterprises to carry out nucleic acid detection and implement the relevant requirements for epidemic prevention and control of imported cold chain food in the business places involved in the trajectory of convection adjustment.

The recent local epidemic in Chengdu is mainly related to large-scale farmers’ markets, tea houses, bars and freight stations.

Fan Shuangfeng, director of the Emergency Office of Chengdu CDC, said that some provinces and cities around Chengdu have already had a certain scale of epidemic, so Chengdu is facing greater pressure from external defense input and internal defense rebound.

At present, based on the requirements of 20 optimization measures, the city’s mobile teams are making full efforts to carry out investigation and disposal of epidemic sites. Judging from the on-site investigation, the recent cluster epidemic in some places is mainly related to some large farmers’ markets, tea houses, bars and freight stations. In these places, in most cases, foreign cases were introduced into places where people gathered, which led to the subsequent spread of the epidemic.

Chengdu Municipal Committee of Social Governance: Citizens need to check their health codes when entering the community yard.

Jiang Wei, deputy director of the Social Governance Committee of Chengdu Municipal Committee, reminded and suggested to the public about the epidemic prevention and control after the introduction of the 20 measures.

Jiang Wei said that optimizing and adjusting prevention and control measures is not to relax prevention and control, but to further improve the scientific and accurate prevention and control. Community epidemic prevention and control needs the cooperation and support of the general public, and advocates that the general public and friends consciously abide by the current community prevention and control requirements and do the following.

The first is to cooperate with the normalization to implement the management of the courtyard gates in the community. At present, a "check" is carried out on all the people who enter the courtyard of the community, that is, the health code of Sichuan Tianfu Health Link is checked. If there is any abnormal health code, such as red code, yellow code or pop-up, citizens and friends are requested to cooperate with the classified management measures such as nucleic acid detection, home health monitoring, home isolation or centralized isolation.

The second is to actively report to the community. If you are a migrant worker who has returned to Chengdu from outside the province, or a person whose case tracks overlap in the city, or an employee who has finished the closed-loop operation in a high-risk position, or received a short message reminder from the disease control department, please take the initiative to report to the community as soon as possible and implement classified control measures as required. If your family and friends have the above situation, please remind or help with community registration.

The third is to strictly abide by community regulations. At present, the management requirements of household isolation in Chengdu are to carry out household isolation for three days for close contacts and entry personnel who have been released from five-day centralized isolation, and to carry out nucleic acid detection on the first and third days respectively, and to carry out household isolation for seven days for personnel in high-risk areas, and to carry out nucleic acid detection on the first, third, fifth and seventh days respectively, and other personnel who need to be brought into the home shall implement management measures according to the prevention and control requirements of professional departments. Please strictly abide by the relevant regulations of home isolation, and do not go out, and cooperate with measures such as nucleic acid testing and daily personal health monitoring.

At present, the requirement of home health monitoring management in Chengdu is to carry out home health monitoring for employees in high-risk positions who are exposed to closed-loop operations for five days, and to carry out home nucleic acid testing on the first, third and fifth days during home health monitoring. Please refuse all visits and do not gather at home. If I don’t have to go out, such as seeing a doctor, I really need to get permission from the community management. When I go out, I don’t go to crowded public places or take public transportation. Other people who need to be included in home health monitoring should be managed according to the prevention and control requirements published by professional departments.

Chengdu citizens can report "one size fits all" and layer-by-layer overweight behavior to 12345.

Huang Hui, deputy director of Chengdu Health and Health Commission, said that Chengdu will intensify the rectification of "one size fits all" and layer-by-layer overweight phenomenon, increase the intensity of notification and public exposure, and ask the general public to continue to supervise the serious consequences. Please report the problems to 12345 in time.

No longer judge the secret connection of the secret connection

Huang Hui introduced that on November 11th, the Comprehensive Group of Joint Prevention and Control Mechanism of the State Council issued the Notice on Further Optimizing the Prevention and Control Measures of COVID-19 Epidemic, and published 20 measures to further optimize the prevention and control work. After the "Notice" was issued, Chengdu immediately studied and implemented the measures one by one. Chengdu has adjusted the management measures for close contact personnel, overflow personnel in high-risk areas, entry personnel and employees in high-risk posts who have finished closed-loop operations as required. The risk areas have been adjusted from "high, medium and low" to "high and low", and close contacts will be judged timely and accurately, and close contact will no longer be judged. The construction of medical resources is progressing in an orderly manner, and the work of vaccination in Covid-19 and drug storage related to treatment in COVID-19 is progressing in an orderly manner.

The public can inquire about the time limit requirements of nucleic acids in different places in the official micro-health office of Chengdu.

Fan Shuangfeng, director of the Emergency Office of Chengdu CDC, said that under the current epidemic situation, Chengdu is still implementing a normalized nucleic acid detection strategy to help early detection and early detection of the epidemic. At the same time, she also reminded the public to pay attention to different places, the time limit for checking the negative certificate of nucleic acid test, the requirement for entering closed spaces, such as bars, KTV, Internet cafes, mahjong rooms, chess rooms and gymnasiums, is to check the negative certificate of nucleic acid within 24 hours, and for cultural and sports venues such as restaurants, museums, swimming pools and indoor stadiums, it is required to check the negative certificate of nucleic acid for 48 hours. For other places, communities, courtyards, enterprises, institutions and public transport, it is required to check the 72-hour negative nucleic acid certificate. For details of the inspection time limit requirements of some related places, you can also pay attention to the Health Chengdu official micro to inquire.

At present, it is autumn and winter, and the climate is relatively cold, which is also a season of high incidence of respiratory diseases. We appeal to the general public and friends to continue to do personal protection, wear masks, wash their hands frequently, ventilate more, gather less, take the initiative to control the trajectory of cases, and cooperate with the prevention and control measures such as nucleic acid testing and health monitoring.

　　Dual-label cards have made great contributions to the development of credit card market in China. When the clearing market in China is about to open, the relevant departments have once again emphasized the market rules that foreign currency single-label cards should follow. Although it has caused some pains to this kind of products, it is still of positive significance to the future credit card market in China.

　　Double-label credit cards with the logos of UnionPay, Visa, Mastercard and other international card organizations printed on the card face will gradually withdraw from the market in the future. A few days ago, the Payment and Clearing Association issued a "Specific Contents of Policies on Single-label Foreign Currency Cards and Dual-currency Cards", requiring banks to stop issuing new dual-label credit cards.

　　It is also reported that the central bank recently convened major banks and related bank card organizations to hold a meeting on the issuance management of foreign currency single-label cards and double-label cards. The meeting emphasized that foreign card organizations can only provide foreign currency bank card clearing services for cross-border transactions before obtaining the qualification of domestic clearing business. The main spirit of the meeting included reaffirming that foreign currency single-label cards can only be kept in foreign currency, and can be used by overseas entities or online merchants, and the domestic use scope is limited to repayment in accordance with the provisions of the State Administration of Foreign Exchange. Any form of transaction within the territory will be regarded as illegal. At the same time, the issuing bank needs to sort out the functions of foreign currency single-label cards that do not meet the regulatory requirements, and the scope of application of new foreign currency single-label cards also needs to be agreed in the agreement.

　　Although it is confirmed that the dual-label bank card will not be able to issue new products, the dual-label card that everyone is using at present can still be used normally, but the dual-label card cannot be renewed after the expiration of the validity period, and it needs to be replaced by a foreign currency single-label card. Therefore, the dual-label card will gradually withdraw from the historical stage of credit cards in China.

　　recall

　　Dual-label cards have been issued in China for 14 years.

　　The so-called double-label card means that two card organization logos appear on a bank card at the same time. For example, there are both UnionPay and Visa logos on the bank card. International card organizations cooperate with UnionPay to issue dual-label cards, and the Bin number starts with foreign card organizations. For example, Visa Kaka number starts with 4, and Master Card number starts with 51-55, but all of them are used in China as the clearing channel of UnionPay, and are settled in RMB. The common dual-currency credit cards are UnionPay +Visa, UnionPay +Mastercard, UnionPay +JCB and so on.

　　It is understood that the first dual-label card was launched by China Merchants Bank in December 2002, which is of epoch-making significance. Lu Jinhua, a senior expert on bank cards, said that dual-label cards are the product of a special era with China characteristics. China’s dual-label card has the characteristics of China, which solves the problem of how domestic residents spend their money overseas and at home when RMB is not freely convertible, and solves the problem of high threshold for traditional credit cards. In less than two years, China Merchants Bank has issued more than 1 million dual-currency cards, which has set a miracle in the industry. Since then, major domestic banks have followed suit and launched their own dual-label cards, bringing the dual-label cards into a period of rapid growth. Cardholders can travel and shop with only one credit card at home and abroad, and they feel very convenient.

　　remove doubts

　　Why stop issuing double-label credit cards?

　　In fact, these measures mentioned above are all aimed at implementing the Measures for the Administration of Bank Card Clearing Institutions jointly issued by the Central Bank and the China Banking Regulatory Commission. Article 22 of the Measures has clearly stipulated that if an overseas institution cooperates with a domestic bank card clearing institution to authorize the issuance of bank cards, it shall adopt the identification code of the issuer of the domestic bank card clearing institution. Overseas institutions shall not engage in RMB bank card clearing business in disguised form through cooperation.

　　Rong 360 credit card analysts believe that the main reason for stopping issuing dual-label credit cards is that it is a product of the transitional period. In the special period when UnionPay did not popularize foreign payment and settlement business and foreign card organizations could not enter China, banks jointly issued dual-currency credit cards with UnionPay and foreign card organizations to facilitate cardholders to pay at home and abroad.

　　At present, the RMB clearing market is about to open, and foreign card organizations are expected to enter China and obtain the corresponding qualifications for payment and clearing, which may also issue their own brand credit cards in China, and require commercial banks to take their own channels for RMB transfer and clearing. It is precisely because there are two card organizations behind a card that the ownership of dual-currency credit cards is controversial. According to international practice, a card can only belong to one card organization, and the card organization is responsible for the transfer and liquidation. Therefore, under the premise that the RMB clearing market is about to open, the suspension of issuing dual-currency credit cards is to "clear the way" for foreign card organizations to enter the domestic market and facilitate the transfer and clearing of various card organizations in the future.

　　In addition, some professionals told the Beijing Youth Daily reporter that the dual-label multi-card is a magnetic stripe card, which is easy to be cloned and stolen, and it is also a technical reason for its withdrawal from the historical stage. After 2002, major card-issuing banks issued a large number of magnetic stripe dual-currency cards, which missed the initial period of chip cards. More and more magnetic stripe dual-currency cards have increased the migration cost and difficulty of credit card chips in China.

　　In Europe, where chip cards have been migrated, many POS machines no longer accept magnetic stripe cards, which makes many domestic cardholders who travel with magnetic stripe dual-currency cards feel inconvenient. The general chip abroad is EMV standard, while UnionPay is POB standard with China characteristics, which cannot be unified on one chip. The popularity of chip cards only supports credit cards with a single settlement channel and logo. In the past, dual-currency cards that can choose settlement network could not be realized on chip cards, let alone migrated to chip cards.

　　So is it possible to issue a dual-label card using UnionPay Bin number? Relevant card organizers told the reporter of Beiqing Daily that this idea is feasible in theory, but it means that all international card organizations have to rebuild their systems overseas, which is very heavy and costly, and it will definitely not be completed in two or three years.

　　affect

　　Consumption abroad needs to bring two cards in the future.

　　The withdrawal of double-label cards from the historical stage also means that the convenience of "one card goes to the world" is over. In the future, if you want to have credit cards issued by UnionPay, Visa and Mastercard at the same time, you must apply for multiple credit cards.

　　Stopping issuing dual-label credit cards has little impact on cardholders who have no overseas credit card demand, but it will be inconvenient for users who often have consumption abroad demand. Because they need to apply for a single-label credit card from international card organizations such as Visa and Mastercard separately for consumption abroad. However, this kind of card can’t be used in China at ordinary times, and only UnionPay cards can be used in China. Therefore, in the past, one card can solve all the domestic and foreign credit card needs, but now it must be done with two cards.

　　In addition, for ordinary cardholders, the existing dual-currency credit cards often carry the card rights of foreign card organizations, and they can also enjoy the card preferential treatment provided by foreign card organizations. After the issuance of dual-currency credit cards is stopped, cardholders can no longer enjoy these rights and benefits if they only use UnionPay single-currency cards.

　　Some insiders said that the issue of stopping the issuance of double-label cards is only a document issued by the industry association for the time being, and there is no red-headed document from the authoritative department. Therefore, at this stage, banks have not stopped issuing new dual-label cards across the board. The existing dual-label cards can also be used normally until the expiration. Therefore, if there is a real demand and the dual-label card is more convenient, you can apply to the bank quickly, so that you can enjoy the convenience of the dual-label card at least in the next five years. Of course, the double-label card is a magnetic stripe card, and the card user needs to pay special attention to the safety of using the card.

　　question

　　Single-label foreign currency cards have limited use in China.

　　However, the issuance of single-label cards in China is not smooth sailing. After the efforts of all walks of life in recent years, we gradually feel the limitations of single-label cards.

　　First of all, the scope of use of single-label cards is very narrow. Apart from being used abroad, it can only be used in some rare places in China, such as high-end star-rated hotels, shopping malls and restaurants. On June 1st, 2015, Visa closed the transactions of Visa single-label cards issued by domestic banks in China. The foreign currency single-label credit card in hand can no longer be used in China except for overseas transactions. For people who don’t go abroad often, this kind of credit card tends to be marginalized. If they apply, they don’t have a chance to use it at ordinary times. If they don’t have a certain number of transactions, they will be charged an annual fee. If you don’t apply, it’s inconvenient to spend money when you want to travel abroad or on a business trip.

　　Secondly, except UnionPay card, other card organizations can’t bind Apple Pay to single-label cards issued in China, and the latest payment technology can’t be applied to these cards, which makes people feel sorry and can only envy friends and relatives abroad. The safety problem in daily consumption cannot be solved by adopting new technology, which makes people feel awkward.

　　Nowadays, many foreign currency single-label cards are issued and promoted under the slogan of "all-currency cards". The so-called all-currency card refers to the fact that the card no longer charges currency exchange fees when spending across currencies abroad. In many people’s eyes, the all-currency card is to spend Japanese yen in Japan, euro in Europe, or Thai baht in Thailand, but this is not the case. Most of the so-called all-currency cards are charged in US dollars and RMB. Generally speaking, foreign consumption is charged in US dollars, domestic consumption is charged in RMB, and some banks directly charge in RMB, regardless of the cardholder’s transactions at home or abroad.

　　Dual-label cards have made great contributions to the development of credit card market in China. When the clearing market in China is about to open, the relevant departments have once again emphasized the market rules that foreign currency single-label cards should follow. Although it has caused some pains to this kind of products, it is still of positive significance to the future credit card market in China.

　　Text/reporter Cheng Wei

Special topic: picture channel

　　Recently, a Japanese TV series "Absolute Boyfriend" adapted from the best-selling comic book of the same name was broadcast, which triggered a hot topic on the Internet. The leading role of the drama "Fast Water Naoko" saved its declining career because of its high ratings. On a website, an item "Do you want to have a robot boyfriend like Knight?" In the survey, 83.74% of netizens voted "very hopeful" on the grounds of "absolute loyalty"!

　　Our reporter Qian Jiayu

　　Netizen argued: Can you accept a robot boyfriend?

　　Robots act according to procedures. Although they are perfect, they are only procedures after all. Whether they can accept robots as boyfriends or not, netizens, like the pear clothes in the play, are never able to accept them and cannot extricate themselves.

　　"Boyfriend is a robot, which is too sad. The human heart is the most sensitive and irreplaceable. The feelings emanating from the human heart affect the perceptual behavior of the whole body. The machine is too cold to exude such mellow feelings!"

　　-Netizen "NONO" can’t accept robots as boyfriends.

　　"In reality, I always worry about my boyfriend’s betrayal and not loving myself. Robot boyfriends like Knight are loyal, so I would rather fall in love with such robots!"

　　-Netizen "Maruko" lamented the lack of love in real life.

　　"Robots are in power because humans don’t know how to love anymore. If a person doesn’t know how to love exclusively, it is different from a robot. And once a robot knows how to love, what is the difference between him and people? "

　　-More netizens reflect on the love in reality from the love of robot boyfriends.

　　"When your lover becomes a robot, your feelings and family can be replaced by a’ thing’ created by human beings themselves. This in itself is a process of materializing human beings, in which materialization is not only life, but also feelings and the whole human society. If humans are infatuated with robots or marry robots, our work and life will become a robot moving, which is definitely a terrible thing! "

　　-rational netizens suggested that robot companions violated human morality and ethics.

　　Pure love touched female fans outside the show.

　　"Absolute Boyfriend" is adapted from the cartoon of the same name by cartoonist Yuu Watase. The story tells that the young OL Pear Clothes of the pastry company have a bad relationship and have customized a robot boyfriend. After the robot is started, according to the customization requirements, they always take good care of Pear Clothes. Pear clothes can’t fall in love with a machine at first, but the robot boyfriend loves her as the only treasure. The play invited popular Japanese idol stars, such as Hayashi Naoko and Saki Aibu, to star in it. Fast water straight starring robot boyfriend Nate, in constant communication, he gradually has human feelings.

　　Knight knows more about love than humans.

　　Many netizens said that the plot of the play is actually a very old-fashioned love theme, and the story based on comics also makes the plot seem naive, but the "pure love" of the robot boyfriend is still very different from the real people, just like the scientist who made Knight in the play, Mr. Che said: "Knight’s pure heart is more human than us humans." Some netizens lamented that people in reality don’t know what true love is because of various interests, and the meaning of "I love you" is still unclear, so they just blurt it out. This seemingly simple Japanese drama may actually want to explore not only love itself, but also how to love this deeper theme.

　　In the play, although Knight is a robot who talks about love all day, from the beginning by running the program to having his own consciousness, he sticks to the idea that he is the best boyfriend of Pear Clothes at all times, and finally desperately leaves evidence that he has survived for Pear Clothes, that is, a video chip recorded for Pear Clothes when he knows that he is about to disappear. At this time, Knight has sublimated love from verbal to instinctive, and even absurd robots can move the audience deeply.

　　Robot boyfriend’s "feat" to make netizens cry

　　"Climbing over the eaves"-the cake company’s new product launch conference is just around the corner, but the cakes can’t be transported due to traffic jams, which can be anxious for pears. In order to help his girlfriend, Knight takes advantage of robots that are different from ordinary people, flying over the eaves and taking back new products, but his actions are too dangerous to damage the machine part! Robot manufacturers came to repair it and sighed again and again: it only takes four days to leave the factory and needs to be repaired.

　　"Battery Exhausted"-Knight and Pear Clothes became closer, but then Knight found that his battery was about to run out. At the end of his life, Knight sincerely asked Chuangzhi to take care of Pear Clothes instead of him for the last time.

　　Experts predict that humans may marry robots in 2050.

　　An artificial intelligence researcher in Britain once boldly predicted that one day in the future, humans will marry robots! And it may be in 2050. The surprising and interesting conclusion is that David Levy, an Englishman, is studying for a doctorate at Maastricht University in the Netherlands, and his direction is the research in the field of artificial intelligence.

　　In his paper "Intimacy with Artificial Partners", he believes that robots will be more and more like humans in appearance, function and personality, so many people may fall in love with robots and even marry them in the future. For this conclusion, David specifically explained that psychologists have basically figured out why humans love each other, including roughly 12 basic reasons, and these reasons are almost equally applicable to the relationship between humans and robots. For example, one of the reasons why human beings love each other is that two people are similar in personality and knowledge, which can be realized by programming. In addition, if you know that another person likes you, people are more likely to fall in love, and this situation can also be achieved by writing programs.

　　"robot love" in film and television

　　China

　　"BAD BOY Attack": In the film, Shu Qi plays a copied robot beauty, and an encounter with Ekin Cheng produces an emotional story. The difference is that Shu Qi is not innocent girl type, but has superb martial arts.

　　Cai Ming and Guo Da’s sketch "Robot": In the sketch, Guo Da bought a robot girlfriend who can cook, and finally the robot girlfriend lost control!

　　Editorial Story: Li Lingyu, the robot girlfriend that Ge You once liked, turns out to be just a female liar!

　　South Korea

　　My Girlfriend is a Robot: This film is another masterpiece directed by My Savage Girlfriend, which describes the love story between a lonely college student and a robot from the future. Ayase Haruka, who plays the future robot in the film, has amazing power under his lovely appearance, but he lacks human emotion because he is a robot.

　　Hollywood

　　Kawara Tsutomu the Robot: This film is the masterpiece of Toy Story Pixar. Specifically, about 700 years later, human beings have made a mess of the earth’s homeland, and robots that listen to program instructions and constantly clean up garbage work around the clock. Years have passed, and the rusty little robot has worked tirelessly and is busy in the garbage dump every day. Optimistic, it has gradually learned to steal time and entertain itself like a human being. Suddenly one day, Eve, a glamorous and beautiful female robot, came down from the spaceship to perform a search task. The two robots "fell in love at first sight" and talked about love.

Editor: Li Dan

1905 movie network news　The film is adapted from the classic original work of the same name and tells the story of affection, love and growth of the four sisters of the March family. Since the release of Christmas in North America last year, the film has won unanimous praise both inside and outside the industry with its emotional core of warm-hearted healing, vivid interpretation of the immortal cast and excellent production by the top Hollywood team, and won six heavy nominations in the 92nd Academy Awards, and finally won the best costume design award.

Among them, "diana frances" Florence Pugh, born in 1996, reshaped the role of Amy, the little sister of Ma Qi’s family in the original work, and won the Oscar nomination for best supporting actress. Little Women was previously withdrawn from the archives in China due to the epidemic, and the date of the archives will be announced another day.

Amy, who is spoiled and ignorant in the original works, has always been a controversial character, but Florence vindicates Amy in the movie Little Women, showing a more real and multifaceted new little sister image. Her self-confidence, rebellion and desire, sober self-awareness and strong personality. Although she dreams of becoming a painter, she can also recognize her lack of talent; Although she insists on the concept that marriage is an economic problem, she can bravely give up the engagement of a rich and powerful family for the sake of man next door Laurie, who has always had a crush on her. Florence accurately depicts Amy’s growing process and complex personality with her strength beyond her age, which shows that the strength of being nominated for the Oscar for Best Female Matching cannot be underestimated.

In addition to the Oscar’s affirmation, Florence’s performance in Little Women has won many praises from the industry and the media. Saoirse Ronan, who plays the second sister Joe, called her portrayal of Amy "unprecedented" and let the audience see "Amy’s struggle"; Director Guilmault del Toro praised her "infinite talent" and her performance "incredible"; Washington post even commented pertinently: "Florence’s performance in Little Women achieved a rare balance. One second she captured Amy’s smart nature, and the next she showed her solemn and reserved behavior."

Florence’s successful shaping of Amy is inseparable from her belief in pursuing realism. Before filming a fight between Amy and Joe, Florence asked Ronan to slap her hard. While filming the scene where Amy fell into the lake while skating, Florence didn’t mind that she had to soak in a big cold pool repeatedly in the cold winter of December. In her own words: "The real feeling of the body helps the performance, and I can’t stand fake things."

Florence Pugh, a 24-year-old British actor, is a dazzling star in Hollywood Ran Ran. In 2017, she won the Best Actress Award at the British Film Awards. In the past two years, it has been her "big year", challenging the horror masterpiece, the masterpiece adaptation film Little Women and the Marvel superhero blockbuster in succession, and trying to broaden the stage. Just recently, in the new preview of Black Widow, she and Scarlett Johansson, a widowed elder sister, were on the same stage to show their extraordinary skills.

In the film, she plays yelena, the younger sister of the black widow. From "little sister" to "widowed sister", she takes the status of "sister professional household". Some netizens ridiculed: "I didn’t expect’ little woman’ Amy to be so able to fight!" It can be seen that the role of Amy is deeply rooted in the hearts of the people. Florence, whose popularity has soared, also appeared on the cover of the famous American fashion magazine VOGUE in February. She has become Hollywood’s new favorite and has a bright future.

Little Women’s lineup behind the scenes is luxurious. The film was adapted and directed by Oscar-nominated director greta gerwig (), and emma watson (Harry Potter series), Saoirse Ronan (Lady Bird) who mentioned four Oscars, and Hollywood rookie Eliza scanlon (Sharp Tool) together with Florence formed "March Sisters Flower", "Sweet Tea" Timothée Chalamet (), four-time Golden Globe winner laura dern () and three-time Oscar winner Meryl Streep ("Washington". Jacqueline Durran, the costume designer of Atonement, Jess Gonchor, the artistic director, and alexandre desplat, the composer, formed the behind-the-scenes team of the Oscar gold medal.

　　When Xiao Hao was three years old, his mother found that his bones became more and more "hard": he couldn’t squat, his arms were difficult to bend, and he was accompanied by hepatosplenomegaly and heart reflux. Sadly, he was never diagnosed … …

　　After six years, Xiao Hao was finally diagnosed — — Suffering from mucopolysaccharide storage type ⅱ, thus, a family knows that there is such a rare disease in the world.

　　May 15th every year is the International Care Day for Mucopolysaccharide Storage. When children have symptoms such as rough face, stunted growth, thick joints, big head, "chicken breast", hepatosplenomegaly, abnormal heart and even mental retardation, they must be careful of Mucopolysaccharide Storage. Mucopolysaccharide, also known as glycosaminoglycan, is a macromolecular substance widely existing in human cells. Mucopolysaccharide is a big family. Your skin is white and tender, your joints are flexible, and your eyes are bright, which is closely related to the members of the "Mucopolysaccharide" family.

　　Although the mucopolysaccharide family is miraculous, there must be a premise that our cells can digest them normally, and the cells have specially prepared a "digestion workshop" — — Lysosome.

　　Lysosomes specialize in degrading foreign or endogenous biological macromolecules, such as lipids, glycogen and mucopolysaccharides, etc., and they can take this big job because of more than 60 enzymes contained in them.

　　More than 60 kinds of enzymes have their own functions, without any one of them, a specific biological macromolecule may not be degraded normally, thus being stored in lysosomes.

　　Lysosomes began to swell, eventually making cells bloated and abnormal, and indigestible macromolecules deposited in various organs of the body, and people’s symptoms became more and more obvious.

　　The reason of enzyme deficiency is often gene mutation. Mucopolysaccharide storage disease (MPS) is a congenital genetic and metabolic disease, which leads to the deposition of this kind of mucopolysaccharides because of the lack of enzymes that decompose the corresponding mucopolysaccharides.

　　According to the different enzymes, mucopolysaccharide storage disease can be divided into seven types and multiple subtypes.

　　Although there are many types, MPS patients have some basic characteristics: multiple organs in the whole body are affected, the development is delayed, and the condition is gradually aggravated; Short stature, rough face, big forehead protrusion, skeletal deformity, thick joints, claw-shaped hands, corneal opacity, otitis media, narrow respiratory tract, hepatosplenomegaly, heart disease, and serious cases will affect intellectual development.

　　There are differences between different types. For example, the majority of patients with type II are men, patients with type III show obvious mental retrogression, and patients with type IV concentrate on skeletal deformity. Similarly, the disease has brought a heavy burden to every patient’s family.

　　Most of the patients with mucopolysaccharide storage disease are children, and they are affectionately called "sticky babies" in China, because the symptoms of MPS are complex and rare, and there may be many undiagnosed MPS patients who are struggling to seek medical treatment in confusion.

　　At first, there was no specific treatment for MPS, and only symptomatic treatment could relieve the pain. In recent years, enzyme replacement therapy has become an effective treatment for some MPS. Simply put, it is "what enzyme is lacking".

　　In recent years, with the country’s increasing attention to rare disease groups, the research and development or introduction of drugs for rare diseases is accelerating. At present, MPSⅣA has become the first MPS therapeutic drug approved for marketing in China. Type I and type II drugs are also expected to be listed in China soon. Type III drugs are still under development; However, as far as the drugs on the market are concerned, they are expensive. Without medical insurance, ordinary families will face an unbearable situation.

　　If we can use specific drugs from an early age, Sticky Baby can enjoy a high-quality life like us. Even if they can’t take medicine, there are still many MPS patients who insist on going to school or work actively, playing their own part.

　　May 15th every year is the International Care Day for Mucopolysaccharidosis. The MPS family in trouble needs everyone’s attention and support. Let’s join these lovely "sticky babies" and hope that the day when medicine can be used will come soon!

　　Medical Guidance: Chief Physician Zhang Huiwen

　　Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine

　　Shanghai Institute of Pediatric Medicine

　　Shanghai Children Rare Disease Treatment Center

　　References:

　　[1] Zhang Huiwen, Wang Yu, Jun Ye, Qiu Wenjuan, Han Lianshu, Gao Xiaolan, Gu Xuefan. Common enzymatic classification of 47 cases of mucopolysaccharide storage disease [J]. Chinese Journal of Pediatrics, 2009,47 (4): 276-280.

　　Shi Huiping. Case diagnosis and prenatal diagnosis of lysosomal storage disease [J]. Chinese Journal of Pediatrics, 1999,37 (1): 57-58.

　　Wu Xiru, Bao Xinhua. Progress in diagnosis and treatment of lysosomal storage disease [J]. Journal of Peking University (Medical Edition), 2005,37 (4): 440-444.

　　Tian Zhiqiang, Ji Shengli. Relationship between glycosaminoglycans and inflammation [J]. Chemistry of Life, 2005,25 (6): 485-487.

　　(Written by Hao Yu, Illustrator/Mai Chuan)

Price Trend Analysis of Tesla Model Y

Recently, Tesla’s Model Y has continued to sell well in the global market, showing its potential as one of the hottest models this year. According to statistics, as of September this year, the sales volume of Model Y has exceeded 500,000 units, which undoubtedly verified its strong appeal among global consumers.

Price differences in different regions

According to Tesla official website, the price difference is significant around the world. Xiao Lei pointed out that Singapore is one of the highest-priced markets in the world, and the basic price of Model Y is S $142,471 (about RMB 747,183), excluding taxes. In contrast, Chinese mainland is the cheapest market in the world. After the price reduction, the price of Model Y has dropped to 288,900 RMB, which is amazing compared with the Singapore price. This gap is mainly due to the tax policies and market control strategies of various countries, such as Singapore’s high tariffs and automobile growth control measures.

In China, due to the vigorous development of the new energy vehicle market, overseas brands such as Tesla enjoy policy support, and their prices are relatively low. However, with the rise of local new energy brands such as BYD, Weilai and Ai ‘an, the market competition is becoming more and more fierce. Tesla needs to constantly adjust its strategy, such as launching new models and promotional activities, to maintain its market share.

Tesla’s Challenges

Although Tesla takes the lead in the new energy vehicle market, its competitiveness is gradually facing challenges with the slowdown of product update. With the continuous emergence of new products from other brands, Tesla needs to accelerate the pace of innovation and provide more competitive products in order to gain a foothold in the increasingly fierce market competition. In order to maintain market popularity, Tesla recently launched two new car paint colors: Fast Silver and Midnight Crimson, but this is only a short-term strategy. In the long run, a strong product line is the key to maintaining competitiveness.

Generally speaking, the price trend of Tesla Model Y reflects the global market demand and policy impact, and also indicates Tesla’s future challenges in the field of new energy vehicles. In the face of fierce competition in the market, Tesla needs to constantly innovate and launch competitive new models to cope with future market changes.

The price of Buick varies with different models. If you are interested in the price of Buick, you can refer to the price range of the following models:

The price range of Buick GL8 is232,900 yuan to 473,900 yuan; The price range of LaCrosse is179,900 yuan to 239,900 yuan; Angkewei’s price range is196,900 yuan to 259,900 yuan; The price range of the century is469,900 yuan to 689,900 yuan; Regal’s price range is159,800 yuan to 175,800 yuan; Weilang’s price range is128,900 yuan to 158,900 yuan; The price range of Buick E5 is169,900 yuan to 213,900 yuan; Angola’s price range is126,900 yuan to 136,900 yuan; The price range of Angke Banner is299,900 yuan to 359,900 yuan; The price range of Buick GL8 new energy is359,900 yuan to 419,900 yuan; The price range of light blue 6 is112,800 yuan to 168,900 yuan; The price range of Buick E4 is159,900 yuan to 229,900 yuan; The high-spirited price range is152,900 yuan to 178,900 yuan.

It should be noted that the above prices may change due to regions, distributors and market conditions. If you need more accurate price information, it is recommended that you contact your local Buick dealer directly for consultation.

If you don’t consider the later cost of the car when you buy a car, you will regret it later. For example, the performance in this regard mentioned today is worth mentioning. The strength of the car still needs to be understood before you know it. Let’s take a look together.

Take a look at the appearance of the Peugeot 2008 first. The front face of the Peugeot 2008 looks more angular and sporty. With the simple headlights, the overall look has a certain sense of hierarchy. The car is equipped with LED daytime running lights, delayed shutdown, etc. To the side of the body, the body size of the car is 4312MM*1785MM*1545MM. The car adopts dignified lines, and the side circumference gives a very avant-garde personality. With large-sized thick-walled tires, smooth lines run through the entire side of the car. Looking back, the overall shape of the rear of the car echoes the front face. The taillights show a delicate design style. Coupled with the unique exhaust pipe, the overall look is very avant-garde personality.

Sitting in the car, the interior style is very soft and the visual effect is very good. The steering wheel of the car is very in line with the interior style, equipped with the steering wheel manual up and down + front and rear adjustment, and other functions, which is full of design sense. Let’s take a look at the central control, the car is decorated with a simple touch LCD central control screen, which makes the interior design quite layered, and the details are still in place. The dashboard and seats are also eye-catching, and the car is equipped with a sharp dashboard, highlighting the trendy temperament. The car adopts imitation leather seats, and the seats are wrapped in place, making it very comfortable to ride.

Peugeot 2008 is equipped with a wet dual-clutch (DCT) gearbox with a maximum power of 100KW and a maximum torque of 230N.m, resulting in good power performance.

In addition, the car is equipped with driving mode selection, remote key, rear wipers, engine start-stop, traction control (ASR/TCS, etc.), and other configurations.

This level of models is usually the first choice for most people. Firstly, the price is not expensive, and secondly, all the configurations are quite complete, which is still very worth buying. Interested riders might as well go offline to experience it.